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Can I just stop taking hormone replacement therapy? When a woman stops taking HRT, menopausal symptoms may come back. Stopping HRT can be done suddenly or gradually. When HRT is stopped gradually, the dose is tapered down to nothing over time. 91% recommended gradually stopping HRT.
Where is estradiol made? During the reproductive years, most estradiol in women is produced by the granulosa cells of the ovaries by the aromatization of androstenedione (produced in the theca folliculi cells) to estrone, followed by conversion of estrone to estradiol by 17ОІ-HSD.
Is weight gain a side effect of estradiol? Many women notice that they gain weight during this time in their life. One reason why people might gain weight around menopause is changing hormone levels. One form of estrogen called estradiol decreases at menopause. Lower levels of estradiol may lead to weight gain.
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