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What type of hypersensitivity is transplant rejection? Hyperacute rejection is characterized by ischemia and necrosis of the graft that occurs from the time of transplant to 48 hours after transplant. It is believed to be caused by cytotoxic antibodies present in the recipient that respond to tissue antigens on the donor organ.
What happens when body rejects kidney? Rejection is a normal reaction of the body to a foreign object. When a new kidney is placed in a person's body, the body sees the transplanted organ as a threat and tries to attack it. The immune system makes antibodies to try to kill the new organ, not realizing that the transplanted kidney is beneficial.
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