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Should eltroxin be taken on empty stomach? Because of this, patients are usually instructed to take levothyroxine on an empty stomach 30-60 minutes before food intake to avoid erratic absorption of the hormone. This is often difficult for many patients, especially those on multiple medications. Is thyroid medication covered by insurance? Tirosint (levothyroxine) is an expensive drug used to treat hypothyroidism. It also treats an enlarged thyroid gland and thyroid cancer. This drug is less popular than comparable drugs. Tirosint is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.
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